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Objective To study the rehabilitation effect of aripiprazole in patients with schizophrenia and the satisfaction of family members. Methods 64 patients with schizophrenia were randomly selected from the two groups. The control group and the observation group were randomly divided into two groups: the routine management and the cooperative nursing management model, and the social function evaluation scale and Family satisfaction questionnaire to investigate the results of the two groups of patients with the rehabilitation effect. Results The scores of rehabilitation questionnaire scores and family satisfaction scores in the experimental group were higher than those in the conventional condition (P<0.05), which indicated that the cooperative nursing model was helpful for the rehabilitation of schizophrenia. Conclusion The use of synergistic nursing model in the treatment of aripiprazole has a great effect on the rehabilitation of patients with schizophrenia. The results are very good.
ABSTRACT
Objective To study the rehabilitation effect of aripiprazole in patients with schizophrenia and the satisfaction of family members. Methods 64 patients with schizophrenia were randomly selected from the two groups. The control group and the observation group were randomly divided into two groups: the routine management and the cooperative nursing management model, and the social function evaluation scale and Family satisfaction questionnaire to investigate the results of the two groups of patients with the rehabilitation effect. Results The scores of rehabilitation questionnaire scores and family satisfaction scores in the experimental group were higher than those in the conventional condition (P<0.05), which indicated that the cooperative nursing model was helpful for the rehabilitation of schizophrenia. Conclusion The use of synergistic nursing model in the treatment of aripiprazole has a great effect on the rehabilitation of patients with schizophrenia. The results are very good.
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<p><b>OBJECTIVE</b>To determine the optimum treatment for viral myocarditis (VMC).</p><p><b>METHODS</b>A total of 126 VMC patients were randomly divided into the control group (42 cases) that was treated with conventional Western medicine, and the intervention group (84 cases) that was treated with a combination of Chinese medicine (CM) and Western medicine intervention termed optimum proposal of integration of disease and syndrome (OPIDS). Before and after 4 weeks of treatment, the integral of CM syndrome, self-rating depression and anxiety scales (SDS and SAS, respectively), echocardiograms (ECGs), heart rate variability and left ventricular systolic function were observed.</p><p><b>RESULTS</b>Compared with the control group, the intervention group showed significant reductions on the SDS and SAS (P <0.05); improvement of premature ventricular beats, atrioventricular blocks, ST-segment abnormalities, and significant T wave changes (P <0.05); greater reductions in standard deviation of NN intervals (SDNN), standard deviation for per 5 min averages NN intervals (SDANN), and root-mean-square of successive difference of NN intervals (rMSSD) (P <0.05); and increases in cardiac output, stroke volume, and ejection fraction, the last of which was statistically significant (P <0.05). Overall, the treatment efficacy rate was significantly better P<0.05) in the intervention group (75.61%) compared with the control group (69.70%).</p><p><b>CONCLUSION</b>OPIDS is quite effective in treating VMC and improves symptoms such as anxiety and depression, left ventricular systolic dysfunction, premature ventricular contraction, and cardiac autonomic nervous system dysfunction. [</p><p><b>REGISTRATION</b>Chinese clinical trial center (No. ChiCTR-TRC-00000298)].</p>
Subject(s)
Adolescent , Adult , Female , Humans , Male , Young Adult , Anxiety , Depression , Electrocardiography , Heart Rate , Medicine, Chinese Traditional , Myocarditis , Diagnostic Imaging , Therapeutics , Virology , Syndrome , Systole , Ultrasonography , Ventricular FunctionABSTRACT
Objective To analyze three different classification criteria, the clinical characteristics of antiphospholipid syndrome(APS)in a cohort of Chinese patients. Methods From January 1996 to October 2006, APS patients diagnosed with different classification criteria were retrospectively studied. Results There were totally 120 APS patients fulfilled at least one criterion, One hundred and one patients fulfilled the 1988 Asherson criteria, 96 patients fulfilled the 1999 Sapporo criteria, and 115 patients fulfilled the 2006 Sydney criteria. The ratio of male to female in a cohort of 115 definite APS patients was 1 to 10.5. The mean period of the disease until entry into the study was 82.6 months, the mean age at study entry was(41?12)years. Ninety patients had thrombosis episodes, among which the most common presenting manifestations were deep venous thrombosis, stroke and skin vasculitis. Forty-six of 92 married women in our cohort had fetal morbidity. Catas- trophic APS occurred in 7 patients. The presence of anticardiolipin antibodies(aCL)was detected in 86 pa- tients, anti-beta-2 glycoproteinⅠantibodies in 58 patients and lupus anticoagulant(LA)in 27 patients. Conclusion The most common presenting manifestations are deep venous thrombosis, stroke and cutaneous manifestations. The sensitivity of Sydney classification criteria is improved by adding anti-beta-2 glycopreteinⅠantibody as one of the laboratory criteria. However, primary APS patients who only presented with thrombo- cytupenia and positive laboratory tests could not satisfy this criterion. In addition, the significance of autoanti- bodies to some coagulant factors in APS needs further study.